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👇 #Siglec-7 NMR assignment and binding studies with #gangliosides, impact of ligand flexibility #nmr #3D #glycan #glycotime #GD3 #structuralbiology #biophysics @robertamarchetti.bsky.social @molinarotony.bsky.social advanced.onlinelibrary.wiley.com/doi/10.1002/...
Apr 26, 2025
The molecular recognition of the sugar moiety of GD3 and Gb3 (globotriaosylceramide) derivatives by Siglec-7 has been thoroughly studied offering insights for cancer diagnostics and therapies. A comb....
advanced.onlinelibrary.wiley.com
Insights into Siglec‐7 Binding to Gangliosides: NMR Protein Assignment and the Impact of Ligand Flexibility
Alba Silipo