Signal Transduction and Targeted Therapy (STTT) | A Nature Portfolio journal | Impact Factor 52.7 | Q1 in Biochemistry, Cell Biology & Molecular Medicine | Open Access
Visit: https://www.nature.com/sigtrans/
Signal Transduction and Targeted Therapy
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Researchers show that enrichment of Streptococcus oralis in the respiratory #Microbiome boosts innate immunity and protects against #Influenza, underscoring the role of respiratory microbial communities in #Antiviral immunity.
#STTT #OpenAccess: doi.org/10.1038/s413...
The ICTAN phase 3 #ClinicalTrial demonstrates that adjuvant icotinib therapy significantly improves disease-free and overall survival with manageable safety in resected #EGFR-mutated stage II–IIIA #NSCLC patients.
#STTT #OpenAccess: doi.org/10.1038/s413...
This study shows that the tumor-suppressive LTFe–LTF axis regulates #Ferroptosis in #ProstateCancer, highlighting this axis as a critical #Epigenetic regulator and potential #TherapeuticTarget for improved treatment outcomes.
#STTT #OpenAccess: doi.org/10.1038/s413...
This review examines how #Glycan-binding proteins influence disease mechanisms and discusses emerging #Glycobiology-driven therapeutic strategies across #Cancer, inflammatory, infectious, and metabolic disorders. @univbordeaux.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
Researchers show that the Gdf15–#Xenobiotic receptor axis drives NK cell maladaptation under environmental stress, contributing to the development of #ColdTumors and offering new insights into tumor #ImmuneEvasion.
#OpenAccess: doi.org/10.1038/s413...
This study shows that the #Anticancer activity of certain #HDAC inhibitors is independent of their ability to inhibit HDAC enzymes, refining current understanding of their mechanisms of action and therapeutic potential.
#OpenAccess: doi.org/10.1038/s413...
Researchers use #scRNAseq to identify the #Prolactin receptor as a #TherapeuticTarget in #Adenomyosis, revealing disease-driving mechanisms and supporting the development of targeted treatment approaches. @pku1898.bsky.social
#STTT #OpenAccess: doi.org/10.1038/s413...
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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Society for Molecular Biology and Evolution
ESMO - European Society for Medical Oncology
International Neuroendocrine Cancer Alliance (INCA)
