Exploring the physiology of host-microbiome interaction
Professor at the Duke University School of Medicine
https://sites.duke.edu/rawlslab/
https://www.linkedin.com/in/john-rawls-71b8118/
John F. Rawls
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Please share w/ interested colleagues this new EMBO Course in Bath UK (6-18 July 2026) “Computational & experimental microbiomics”: lnkd.in/e7EGH4RG
The course includes experimental emphasis on zebrafish host-microbiome interaction + general microbiomics skills. Register is 11 May #EMBOMicrobiomics
Part 6: For decades, the zebrafish has helped scientists unlock the mysteries of genetics, development, & disease. But the fish that power most discoveries have spent generations inside lab tanks. This video captures footage of zebrafish in their natural environment in Nepal.
youtu.be/cCZhZpPALqw
Cherry blossoms in Duke Gardens - a gentle and reliable lesson in impermanence
Happy International Day of Women & Girls in Science! Today & everyday I am grateful for the opportunity to work alongside & learn from this talented group of women scientists. Funded by grants from the NIH, this team is working to understand how the gut microbiome affects our digestive health.
Our EMBO workshop is now live. Visit us in Bath this summer for a two week workshop designed to help you study host-microbe interactions in the zebrafish, and develop the bioinformatics skills needed to analyse the complex data sets that arise from microbiomic studies.
Part 7 & End of Chapter: While waiting for export permits, we explored the Kathmandu Valley—alive with Buddhist & Hindu traditions, temples at every turn, chaotic traffic, hills filled with with monasteries, & endless momos. Fieldwork now complete, the analysis phase begins. Thanks for following!
Part 5: Amid the fieldwork & meetings, this trip also brought our U.S. & Nepali teams closer together. The visit happened to overlap with the Tihar festival, giving us time to see the celebrations firsthand & to share meals & conversations that connected the work to the culture & people around it.
Two new articles from our lab!!
Davis et al identified epithelial transcription factor ELF3 as a key mediator of host-microbiota interaction in zebrafish tinyurl.com/pkavnxdp
Morash et al revealed enteroendocrine cell subtypes in zebrafish & catalogued their peptide hormones tinyurl.com/bdzbm2xm
Enteroendocrine cells (EECs) in the #gut #epithelium secrete diverse hormones that regulate digestion, energy use & behavior. @jfrawls.bsky.social &co identify EEC subtypes & #hormone profiles in #zebrafish, and explore their lineage relationships @plosbiology.org 🧪 plos.io/49iZKWC
John F. Rawls
John F. Rawls
John F. Rawls
John F. Rawls
Edan Foley
Bill Goldman
Enteroendocrine cells (EECs) in the gut epithelium secrete diverse hormones that regulate digestion, energy use, and behavior. This study identifies EEC subtypes and their hormone profiles in zebrafis...
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John F. Rawls
PLOS Biology
The critical contribution of microbiota to animal, plant and environmental health is now widely accepted. Progress has been driven by two parallel approaches: in silico analyses of large -omics data …
