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New work from the Knipscheer group published in @science.org reveals a mechanism involving RNA and DNA repair proteins that helps cells remove G-quadruplex structures. G4 structures are knot-like formations in DNA that can cause damage if left unresolved. www.hubrecht.eu/cells-untie-dna-knots/
Jun 13, 2025
New work from the Knipscheer group reveals a mechanism involving RNA and DNA repair proteins that helps cells safely remove G-quadruplex (G4) structures.
www.hubrecht.eu
Knot good: How cells untie DNA to protect the genome
Hubrecht Institute