New study from Pipsa Saharinen’s lab @pipsasaharinen.bsky.social at #WRIHelsinki, featured on the cover of @jci.org: Integrin conformational switching regulates ANGPT2/TIE2/FOXO1 signaling at endothelial cell junctions.👇
Wihuri Research Institute
What integrins in the cell junction are doing without classical extracellular matrix ligands: doi.org/10.1172/JCI1...
Sipilä et al. present ANGPT2 in complex with TIE2 and α5β1-integrin via integrative structural biology techniques.
