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New study from Taija Mäkinen's lab @taijamakinenlab.bsky.social at the #WRIHelsinki featured on the cover of @natcardiovascres.nature.com: A ‘feedforward’ circuit amplifying upstream TIE2 receptor signalling drives PIK3CA-driven venous malformation - and can be therapeutically targeted in mice.👇
11mo
❤️Our July issue is out❤️Discover an Angiopoietin-TIE2-dependent circuit promoting venous malformations, complex disease modelling in cardiac organoids, regulation of cardiac homeostasis by methyonil tRNA synthetase, and more! www.nature.com/natcardiovas...
11mo
Nature Cardiovascular Research
Wihuri Research Institute