🚨Today our phenotypic screening work with primary human airway basal cells is published @jcellsci.bsky.social!
We found that multiple Wnt activating compounds promote basal cell proliferation and validated 1-azakenpaullone in vivo.
doi.org/10.1242/jcs....
doi.org
Summary: A high-throughput screen of 1429 compounds in primary human airway epithelial cells was used to identify that Wnt pathway-activating compounds increase cell proliferation.