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Good news! If you want to publish in @natimmunol.nature.com that a new immune receptor is expressed by immune cells, you just need scRNAseq and a polyclonal antibody. The big advantage is that
2mo
Here the authors identify CLEC12B, a natural killer cell inhibitory checkpoint that limits antitumor immunity. They also develop a nanobody to target it, activating natural killer cell killing of tumo...
Targeting NK cell CLEC12B enhances cancer immunotherapy - Nature Immunology
www.nature.com
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