Combining proteomics, structure prediction, bioinformatics and cryoET to discover non-canonical bacterial protein translocation-folding complex doi.org/10.1101/2025...
Excited to share that as my group launches across Karolinska Institutet and the University of Helsinki, we’re recruiting postdocs and research assistants to study the nanoscale architecture of lipid flux using in-cell structural biology approaches, including cryo-ET and cryo-CLEM
In another inspiring talk at #EMBOComp3D, Julia Mahamid spoke about recent in-cell cryo-ET results
www.biorxiv.org/content/10.1...
Tired of knowing what you are looking for in your tomograms?
Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos)
Code is on GitHub if you want to try it out
CryoSiam: self-supervised representation learning for automated analysis of cryo-electron tomograms https://www.biorxiv.org/content/10.1101/2025.11.11.687379v1
Check out our preprint! With new molecular mechanisms, 140 subtomogram averages, and ~600 annotated cells under different conditions, we @embl.org were able to describe bacterial populations with in-cell #cryoET. And there’s a surprise at the end 🕵️
www.biorxiv.org/content/10.1...
#teamtomo