Congratulations @landau.bsky.social, breakthrough technology from the lab, now live in
@cellcellpress.bsky.social
Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
New York Genome Center
Check out full text here: www.cell.com/cell/fulltex...
Congrats to Wei-Yu, Sang-Ho @ivanraimondi.bsky.social and the whole team! Gratitude to @themarkfdn.bsky.social @cegs-ica.bsky.social @smahtnetwrk.bsky.social
D&D-seq, a single-cell immune-tethering strategy, captures weak and transient DNA-protein
interactions to enable integrated, genome-wide analysis of transcription factor binding
across chromatin state...
