After a long journey, a paper by my colleagues @maudfagny.bsky.social, John Platig, and Katherine Stone was published today. It builds on our earlier work in eQTL networks and casts polygenic trait selection in the context of regulatory network models, shedding new light on the process. Take a look!
John Quackenbush
I’m happy to share our new paper, just published in @molbioevol.bsky.social , that shows how complex traits heritability and adaptation is supported by mutations holding key local hubs positions in eQTL networks !
doi.org/10.1093/molb...
@ideevl.bsky.social
@johnquackenbush.bsky.social
Abstract. Complex traits are determined by many loci—mostly regulatory elements—that, through combinatorial interactions, can affect multiple traits. Such
