Out now in Science! Our study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵
www.science.org/doi/10.1126/...
Unreliable and underperforming antibodies are a longstanding problem, so while the reveal of apparently manipulated antibody data in Thermo Fisher's catalog was a shock, the frustration it sparked among many researchers is perhaps no surprise.
My reporting:
Are there predictive T2D indicators in existing clinical data? Yes, thx to deep learning
Detection of young-onset type 2 diabetes using deep learning across primary and secondary care: a nationwide, retrospective cohort study - The Lancet Digital Health www.thelancet.com/journals/lan...
Tracking beta cell mass!
springer needs not to be our leadoff hitter. lost the jays the game. #bluejays
if ever a fanbase that shows up at >40K per home game deserved better...
CIHR has launched a trial ballon that suggests shifting to one competition a year. This is the worst idea I have heard in a long time. The only benefit is making top-line success rates look better than they are. Keep it as is, do in-person reviews, and keep the pain in the open.
Not just a critique, an editorial that was published in the ADA's own flagship journal Diabetes Care. The experts included several past ADA Presidents and Award winners.
Page views before the ADA publicized the editorial <300, approaching 10k now. Link below, let's help the ADA get the word out.