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But here is the real kicker: this DNA isn't quiet. Using Massively Parallel Reporter Assays (MPRA), scientists identified 3,127 functional variants actively regulating genes in living populations, influencing skeletal morphology (TRPS1) and viral immune defense (OAS1 and JAK1).
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Do Denisovans live on? Science reveals how archaic DNA actively shapes the immune systems of living Oceanic populations today. Read our analysis!
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Living Archaic Legacies: Functional Denisovan Introgression and Multilineal Hominin Evolution in Oceania
Seth Chagi (World of Paleoanthropology🏺)