Delighted to share our publication in
@bloodjournal.bsky.social where we describe the identification of antifungal itraconazole as a potent inhibitor of mitochondrial metabolism in AML
Great effort by joint first authors Katerina Himonas and Lucie de Beauchamp.
ashpublications.org/blood/articl...
Key Points. Nutrient sensing drug-repurposing screen identifies itraconazole, an FDA-approved azole antifungal, as a mitochondrial metabolism inhibitorItra