New review: Kell, D. B. and Roberts, I. (2026) How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution. Chem Soc Rev, in press. doi.org/10.1039/d5cs... @livuni-ismib.bsky.social
The number of possible variants representing the landscape of a protein sequence of length N residues, made of the standard unmodified proteinogenic amino acids, is 20N; its exhaustive experimental an...
