Check out our preprint in which we determine how a class of potent protein antibiotics specifically kill P. aeruginosa without a need to enter the cell.
doi.org/10.1101/2025...
This is work from my PhD in the lab of @rhyswg.bsky.social and many collaborators who contributed amazing data!
Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...
