We are excited to share our pan-pangenome paper! This is a long time coming work of my postdoc with the incredible @psudmant.bsky.social, and a stellar group of people! I hope you enjoy reading it! And I am excited to talk more more about it this week at #PEQG26!!
www.biorxiv.org/content/10.6...
Excited to share new work on two sex-linked pigment traits in Xiphophorus! This project was led by undergrad @lagiven.bsky.social, who’s worked with me for the last 3(!) years. www.biorxiv.org/content/10.6...
We are actively searching for a postdoc to join the lab! Details provided here - johrilab.org/join
Please share.
I will be at PEQG and will be happy to chat if you're interested!
Complete, haplotype-resolved genome assemblies have provided unprecedented insight into the evolution of structurally complex, rapidly evolving regions of human genomes; however, population-scale pang...
This started in 2019 as daydreamy PhD student musings with Tatsuya Araki. We're as excited as ever about germinal centers as a platform for experimental evolution.
Many thanks to PIs @victora.bsky.social @matsen.bsky.social, co-1st authors Ashni Vora and Tatsuya, and many other key collaborators!
Now published: journals.plos.org/plosbiology/...
New paper about zero-shot predictions of mutational effects. There's a lot of misunderstanding about what such predictions can and cannot do. In brief, they're good at identifying deleterious mutations but bad at predicting fitness improvements. 1/
www.biorxiv.org/content/10.6...
Joana L. Rocha
Tris Dodge
#PEQG26 folks! I will be presenting my postdoc project with @jkpritch.bsky.social and @jeffspence.github.io about inferring population structure dynamics over time with tensor decomposition on ARG. The talk will be at the James Crow Talk session on Wednesday. Look forward to seeing everyone there!
#PEQG26 folks! I will be presenting my postdoc project with @jkpritch.bsky.social and @jeffspence.github.io about inferring population structure dynamics over time with tensor decomposition on ARG. The talk will be at the James Crow Talk session on Wednesday. Look forward to seeing everyone there!
Mutation rates per generation are strikingly similar across germlines of animals and across at least one somatic cell type, suggesting a key role for natural selection in shaping mutation rates. This ...
journals.plos.org
Great talk! Loved the elegant solution to trace and visualize population structure dynamics
Parul Johri
johrilab.org
I am recruiting PhD students for my new lab housed in the Sam Noble Museum at University of Oklahoma! If you are interested in fish macroevolution, geometric morphometrics, specimen-based research & phylogenomics please reach out. More info here: fishdiversitylab.weebly.com
Please share widely!!!
Antibody affinity maturation results from a somatic evolutionary process that takes
place in the germinal center. A “parallel replay” experiment on germinal center B
cells reveals the evolutionary for...
Deep learning models have emerged as promising tools for navigating mutational landscapes in protein engineering. These models can be used to predict mutation fitness without the need for task-specifi...
Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social,
@natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n
Siyuan Feng
Germline mutation rates per generation are strikingly similar across animals, despite vast differences in life histories. Analogously, in at least one somatic cell type, mutation rates at the end of l...
Sex-linked traits are widespread, but their genetic architecture has been challenging to characterize, due in part to the repetitive and structurally complex nature of sex chromosomes. In swordtails a...
#PEQG26 folks! I will be presenting my postdoc project with @jkpritch.bsky.social and @jeffspence.github.io about inferring population structure dynamics over time with tensor decomposition on ARG. The talk will be at the James Crow Talk session on Wednesday. Look forward to seeing everyone there!
