We (@sobuelow.bsky.social) developed AF-CALVADOS to integrate AlphaFold and CALVADOS to simulate flexible multidomain proteins at scale
See preprint for:
ā Ensembles of >12000 full-length human proteins
ā Analysis of IDRs in >1500 TFs
š doi.org/10.1101/2025...
š¾ github.com/KULL-Centre/...
AF-CALVADOS: AlphaFold-guided simulations of multi-domain proteins at the proteome level https://www.biorxiv.org/content/10.1101/2025.10.19.683306v1