Do you think that cooperativity requires more than one binding site or subunit? Or just want to read about an interesting enzyme for which both gain- and loss-of-function variants can cause metabolic disease?
Then check out @sarahgersing.bsky.social's review on glucokinase: doi.org/10.1016/j.ti...
Kresten Lindorff-Larsen
... wait! There's more great Review content!
☘️ mechanisms of #SAM homeostasis (Ben Tu et al)
☘️ glucose sensing by #glucokinase and how disease variants impact its function @sarahgersing.bsky.social @lindorfflarsen.bsky.social @rhp-lab.bsky.social
