This is truly fascinating, excellent paper. Likely true for a great many diagnoses, which we totally miss by including all cases in GWAS and adjust for age
Luke Pilling
Age at diagnosis is gaining attention in autism research.
AaD is heritable, with genetic factors influencing whether someone is diagnosed earlier or later. The genetic correlation is only moderate, suggesting differing genetic profiles.
Commentary: doi.org/10.1038/d415...
#autism #genetics
Analyses of symptoms and genomic data indicate that autism that manifests in early childhood is distinct from autism that is diagnosed later in development.
