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We combine the power of C–H activation + red-light photoredox catalysis to unlock a new prodrug logic, based on the masking/unmasking of C–H bonds, which is operative in living contexts.
4mo
10mo
Congrats to Elliott, @hls111.bsky.social, Olivera, Patrick, Alexander and Daniel! Ligand Design Enables the Palladium-Catalyzed Intermolecular Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation @jacs.acspublications.org pubs.acs.org/doi/full/10....
Mauro Mato
#CiQUS researchers have just published a JACS communication reporting an unconventional strategy to uncage drugs in live settings, based on a photoredox unmasking of aromatic C–H bonds Congratulations to the authors on this outstanding work! pubs.acs.org/doi/10.1021/... #FondosEuropeos #RedeCIGUS
Morandi Research Group
4mo
🔓Don't miss #OpenAccess research in our New Talent collection from María Tomás-Gamasa, José L. Mascareñas, @mauromato.bsky.social & co. at @ciqus.bsky.social describing the red-shifted photoredox generation & trapping of alkyl radicals towards bioorthogonality #orgchem
7mo
Very glad to finally share this one, my project at @ciqus.bsky.social during my initial postdoc period, culminated through an outstanding bio collab with Adrián and Alba from MetBioCat. Congrats all!!
4mo
Organic & Biomolecular Chemistry