Congratulations to @aragucci.bsky.social and @sadieantine.bsky.social for their nuclease-NTPase work now online in final form at @natmicrobiol.nature.com
www.nature.com/articles/s41...
A large-scale, comparative cell biology and biochemical screen defines the molecular features controlling antiphage defence systems that encode nuclease effectors and accessory NTPase proteins.
Starting the lab Bluesky account to share a preprint from @aragucci.bsky.social and @sadieantine.bsky.social that reveals molecular principles shared across diverse nuclease-NTPase anti-phage defense systems in bacterial immunity (1/7)
www.biorxiv.org/content/10.1...
Bacteria encode an enormous diversity of defense systems including restriction-modification and CRISPR-Cas that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstra...
