An interesting new study, by Clare Smith’s lab and me, here at Duke. We found that during Mtb infection, CCR6 knockout mice (on a B6 background) form necrotic pulmonary granulomas, have increased IL17 production and have sex specific differences in susceptibility.
journals.asm.org/doi/10.1128/...
An estimated 10.8 million people worldwide were infected with tuberculosis (TB) in
2023, and among those cases, 1.25 million people succumbed to disease (1); 90% of people who become infected with Myc...