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Human TB granuloma transcriptional blueprints show they are dominated by SPP1 macrophages. spp1 is essential for granuloma formation in zebrafish.
journals.asm.org/doi/10.1128/...
Tuberculosis is the world’s most deadly single-pathogen infection. Its causative bacterium,
Mycobacterium tuberculosis, sickens over 10 million people annually. Mycobacterial granulomas are the pathol...
