Inlay

Biologist•writer•humanist•Bardolator•dad•granddad•bicyclist Director, Client Relations & Educational Programs, Life Science Editors (LifeScienceEditors.com) https://linktr.ee/sfmatheson He/him Previous: Cell Reports, PLOS I have friends everywhere.

1/10 For decades, cellular aggregation was considered an evolutionary dead end. Cells could come together temporarily. But complex multicellular organisms like animals? Our study, led by JP Gerdt, with Ruibao & @jennahed.bsky.social suggests it may be time to rethink that🧵 #ProtistsOnSKy

It's Leading Edge Fellow day!!! This day fills me with joy and inspiration. This cohort holds a special place in my heart because it is named for Zara Weinberg, a beloved Leading Edge Fellow who was a visionary scientist and fierce advocate for building a better scientific ecosystem

Scientists on moving past being stuck: "Basically I'm just a lazy son of a bi*ch" – they would play music or paint and at some point that would free their mind up enough that they'd get past their block and then come back to the problem. – Root-Bernstein on the Night Science Podcast

✨Rare model organisms can teach us how to build a body differently. In snail embryos blastomeres can be as big as the rest of the embryo! 🐌Phrontis vibex blastula stained for tubulin (gray), phalloidin (blue) and histone (magenta). 🔬 #ModelMonday #DevBio 📸: Clemens Cabernard

Our new paper is out this week in Nature Neuroscience! www.nature.com/articles/s41... We built a BCI that works with the brain's natural geometry — and we found that people could learn to play a video game with their brains in <1 hr of training. This efficiency is groundbreaking & here's why:

1/11 Happy to share our TICS paper on using the flexibility of one of the most basic cognitive functions, perception, to understand one of the most complex cognitive dysfunctions, psychiatric conditions (also my first formal work in computational psychiatry 🎉) 📄: www.cell.com/trends/cogni... 🧵 : 👇

Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...

New paper out! For decades there has been a ‘standard model’ for gamma oscillations. This upends that model - PFC gamma oscillations are not one thing. Rather they dynamically recruit diverse cell type-specific synchrony motifs to implement multiple functions: www.sciencedirect.com/science/arti...

Busch et al. use nonlinear neural manifolds to help humans gain rapid control over a noninvasive brain–computer interface, allowing them to learn how to play a video game with real-time fMRI neurofeed...

We are thrilled to announce the 2026 Zara Weinberg Leading Edge Fellows! 40 remarkable postdocs pursuing transformative research in biological/biomedical sciences. This is the 7th Leading Edge cohort and we are so excited to welcome them! www.leadingedgesymposium.org/fellows/

Excited to share the first pre-print from our lab!! Check it out here! www.biorxiv.org/content/10.6... We found that many RNA-binding proteins canonically understood to regulate RNA processing can also function like transcription factors and cofactors to directly regulate transcription.

Perceptual multistability, observed across species and sensory modalities, offers valuable insights into numerous cognitive functions and dysfunctions. For instance, differences in temporal dynamics and information integration during percept formation often distinguish clinical from nonclinical populations. Computational psychiatry can elucidate these variations through two primary approaches: (i) Bayesian modeling, which treats perception as an unconscious inference, and (ii) an active, information-seeking perspective (e.g., reinforcement learning), which frames perceptual switches as internal actions. Our synthesis aims to leverage multistability to bridge these computational psychiatry subfields, linking human and animal studies as well as connecting behavior to underlying neural mechanisms. Perceptual multistability emerges as a promising noninvasive tool for clinical applications, facilitating translational research and enhancing our mechanistic understanding of cognitive processes and their impairments.