In our newest preprint we map degrons for >5,000 cytosolic proteins and we develop a degron predictor that can predict novel degron formation, a potential mechanism of pathogenicity. Many thanks to @rhp-lab.bsky.social, @lindorfflarsen.bsky.social and @dougfowler.bsky.social for their supervision.
Degrons are short protein segments that target proteins for degradation via the ubiquitin-proteasome system and thus ensure timely removal of signaling proteins and clearance of misfolded proteins fro...
