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The sudden jump from low to high tractions could act like a switch to trigger tissue spreading, e.g. through the active wetting transition (see below), in processes such as embryo implantation, wound healing, and tumor invasion. www.nature.com/articles/s41...
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An analogy with wetting has proven apt for describing how groups of cells spread on a substrate. But cells are active: they polarize, generate forces and adhere to their surroundings. Experiments now ...
www.nature.com
Active wetting of epithelial tissues - Nature Physics
Ricard Alert Zenón