Back-to-back manuscripts from the Jacobsen and Law labs revealing TFs that direct RdDM! Genetics controlling epigenetics. Reminiscent of KRAB ZFs... shorturl.at/TE4PH shorturl.at/QEHDU
DNA methylation is maintained by forming self-reinforcing connections with other repressive chromatin modifications, resulting in stably silenced genes and transposons. However, these mechanisms fail ...