@mathildemathieu.bsky.social @ivaskalab.bsky.social New discovery from us! Leupaxin, a paxillin family member typically expressed in immune cells, negatively regulates durotaxis and mechanoresponsiveness in metastatic breast cancer cell variants and in cells cultured on soft ECM lnkd.in/diEk8DSR
I am very excited to share this preprint which has been my main postdoc project! We identified leupaxin as a negative regulator of durotaxis via paxillin-FAK inhibition in MDA-MB-231 brain and bone tropic metastatic variants. www.biorxiv.org/content/10.6...
What music should we play to our cells? This was the start of an amazing journey from @ivaskalab.bsky.social at @turkubioscience.bsky.social with Jasmin Kaivola and collaborators @sarawickstrom.bsky.social and others to explore larynx cancer mechanosensitivity!
www.nature.com/articles/s41...
There is a permanent positon open at our centre. Read more & apply 👉 ats.talentadore.com/apply/erikoi...
Introductory post on 🦋! We're a research group headed by Prof. Johanna Ivaska interested in understanding how integrins contribute to every step of cancer progression. We're located at the Turku Bioscience Center in Turku, Finland! Find out more about us and our interests here: ivaskalab.utu.fi
🚨 Job Alert! 🚨
We have an opening at our Microscopy Core Facility in Turku 🇫🇮.
If you love imaging 🔬 and helping scientists succeed, we want you! 👇
abo.rekrytointi.com/paikat/index...
#Microscopy #ScienceJobs #CoreFacility #Imaging
@turkubioscience.bsky.social
Proud to be part of this cool story by @follainga.bsky.social, led by @guijacquemet.bsky.social and @johannaivaska.bsky.social.
Go and have a look!
FlowVision:
@guijacquemet.bsky.social @johannaivaska.bsky.social et al describe a fast label-free live imaging approach revealing key principles of cancer cell arrest on endothelial monolayers–such as flow dynamics & CD44 interaction with matrix hyaluronic acid
link.springer.com/article/10.1...
This link will take you to a page that’s not on LinkedIn
Vocal fold cancer tumours lose some of their malignant traits when mechanically stimulated by physiological stretch or vibrations, mimicking the opening and closing of vocal folds and phonation.
www.nature.com
Postdocs wanted - Please spread the word! We are looking for one bioinformatician and 1-2 cell biologists with different expertise! See the job ad below for more information and links to the job descriptions!
Johanna Ivaska
Integrins, matrix, motility and mechanotransduction in cancer
I will be recruiting two postdocs early next year.
- One image analyst
- one biologist interested in working on lymphatics!
Reach out if you are interested 👍
The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i...
link.springer.com
Turku Bioscience
Michal Dibus
Ivaska Lab
The EMBO Journal
Guillaume Jacquemet
Delighted to share the latest paper from the lab
"Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers"
Amazing work driven by @follainga.bsky.social with contributions from many.
link.springer.com/article/10.1...
Ivaska Lab
Guillaume Jacquemet
The Center is a wonderful collaboration with scientists extraordinaire @taijamakinenlab.bsky.social Kari Vaahtomeri and Cecilia Sahlgren.
We are all recruiting, so keep an eye on our website If you are looking for a postdoc position 😀
The rapid, transient, and unpredictable nature of interactions between circulating cells and the endothelium challenges the investigation of these events under flow conditions. Here, we developed an i...
I am delighted to introduce our new Centre of Excellence in Immune-Endothelial Interfaces (IMMENs) funded by the Research Council of Finland.
www.helsinki.fi/en/researchg...
I will be recruiting two postdocs early next year. One image analyst and one biologist interested in working on lymphatics!
The overarching aim of IMMENs, a Research Council of Finland funded Centre of Excellence, is to understand how local immune responses are regulated at the lymphatic endothelium-immune cell interface.
