Our new paper is out today in AJHG! We applied a "footprinting" algorithm to ATAC-seq data from 170 livers to find non-coding variants associated with TF binding. We show that these "footprint QTLs" (#fpQTLs) can fine-map GWAS loci at base-pair resolution.
www.cell.com/ajhg/fulltex...
Dudek et al. use chromatin accessibility data in liver from 170 human donors to measure
transcription factor binding at genetic variants. They observed 809 variants associated
with binding. Given bind...
