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Parasitic worms & immunity. πŸͺ±πŸ”¬ Avian & human schistosomes. πŸ­πŸ¦† Swimmer's itch, lungs & liver granulomas. πŸŠπŸ»β€β™‚οΈπŸ« Assistant professor at @sciencecharles.bsky.social.πŸŽ“ Secretary of @parazitologiecz.bsky.social. πŸ—’οΈ
Tomas Machacek









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First evidence of biofluorescence in the fire salamander! πŸ–€πŸ’› Under UV light, they show striking blue-green and yellow fluorescence in their skin, glands, and secretions. 🦎✨🌟 @royalsociety.org royalsocietypublishing.org/rsos/article...
Schistosome eggs are not the same in the liver and the intestine πŸ₯šπŸ¦  Following our previous β€œwinners & losers” story, we now provide additional evidence by analyzing proteins released by eggs across different tissues! πŸ”¬πŸ§ͺ www.frontiersin.org/journals/cel...
@charlesuni.cuni.cz is ready πŸ’ͺπŸ»πŸŽ„
PF 2026 πŸ₯³ @parazitologiecz.bsky.social
Where would the Arabs have reached if not for the plague that decimated the Byzantine Empire? And how did malaria influence the fight for American independence? πŸ€” A light yet fascinating read about the germs that shaped our past β€” a perfect blend of infection and history. πŸ“–πŸ¦ 
Attending @bspparasitology.bsky.social Spring Meeting remotely this time πŸ₯² Not ideal, but still excited to share our latest work on Schistosoma mansoni egg secretome directly in the host tissues! πŸ”¬ 🚨 Key message: liver is not intestine 😏
Happy to contribute to the Parasite of the Month series in @cp-trendsparasitol.bsky.social with our article on the neurotropic schistosome Trichobilharzia regenti! πŸ§ πŸ”¬ authors.elsevier.com/a/1m5yH5Eb1x...
@pnas.org Tattoo ink doesn’t just stay in the skin. 🎨 It drains into lymph nodes (kinda expected), where it can persist for months. πŸ€” Ink-loaded macrophages trigger long-term inflammation and can alter vaccine responses. πŸ’‰ www.pnas.org/doi/10.1073/...
Skin-penetrating nematodes rely on dopamine signaling to invade their hosts. Blocking dopamine signalization could stop infections before they start. πŸ”¬ @natcomms.nature.com πŸ”— www.nature.com/articles/s41...
We found maternal helminth infection can promote antiviral immunity in offspring 🀱πŸͺ± www.cell.com/cell-host-mi... Don’t worry, we are not suggesting we reinfect everyone with worms! Instead, we identified a microbiota-derived metabolite, Indole-3-propionic acid, that enhances antiviral immunity!
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Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Tomas Machacek
Ai Ing Lim
Fernandes et al. show that maternal helminths, long-standing mammalian partners, confer antiviral immunity to offspring via the microbiota-derived metabolite indole-3-propionic acid (IPA). This work r...
www.cell.com
Maternal helminths rewire the microbiota to promote offspring antiviral immunity
Abstract. With advances in imaging technologies and the growing availability of specialized lights and cameras, biofluorescence is increasingly recognized
Glandular biofluorescence in fire salamanders (Salamandra salamandra): first evidence and ecological implications
royalsocietypublishing.org
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination | PNAS
Despite safety concerns regarding the toxicity of tattoo ink, no studies have reported the consequences of tattooing on the immune response. In thi...
www.pnas.org
Skin-penetrating nematodes infect hosts by burrowing through host skin. This study finds that in the human-parasitic, skin-penetrating nematode Strongyloides stercoralis, skin penetration behavior is ...
www.nature.com
Dopamine signaling drives skin invasion by human-infective nematodes - Nature Communications