Microglia protect the fetal brain from Zika virus, while primitive macrophages and monocytes drive infection and inflammation, highlighting diverse immune roles. Plus other great insights.
Great work from @stjohnlab.bsky.social
www.cell.com/cell/abstrac...
Fetal microglia are protective against Zika virus, but primitive macrophages and monocytes promote neuroinflammation and are disease promoting. Different fetal immune and neuronal cell types are targeted by different Zika lineages.