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by @danabra.mov
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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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Very happy to share our latest publication unravelling how the #ERstress sensor ATF6 stirs up trouble (and tumors) in #colorectalcancer. ATF6 drives CRC by reshaping lipid #metabolism and the intestinal #microbiota. A huge thank you to all co-authors! #lifesciences www.nature.com/articles/s42...
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www.nature.com
The transcription factor ATF6 causes an enrichment in long-chain fatty acids in the colonic epithelium, which leads to changes in the gut microbiota and contributes to the development of colorectal ca...
ATF6 activation alters colonic lipid metabolism causing tumour-associated microbial adaptation - Nature Metabolism
Olivia Coleman