Teif lab at the University of Essex. We work on gene regulation in chromatin and applications to liquid biopsies, using approaches of genomics, biophysics, bioinformatics & AI. Our focus is nucleosomics, TF binding, CTCF, cfDNA. https://generegulation.org
Teif lab
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Did you know that Pierre Chambon's laboratory was the first to use the term "nucleosome" in 1975 ?
www.cell.com/cell/fulltex...
The +1 nucleosome functions in Pol II transcription initiation and the transition to elongation www.biorxiv.org/content/10.6... [Yumeng Zhan, Julio Abril-Garrido, Frauke Grabbe, Paulina Seweryn, Ute Neef, Christian Dienemann, Patrick Cramer]
Great preprint by @vram142.bsky.social & Co www.biorxiv.org/content/10.6... "fiber homotypy," where chromatin fibers with similar nucleosome spacing interact more frequently in 3D
--> Related to our previous "nucleosome homology recognition" in chromatin royalsocietypublishing.org/rsif/article...
Tested LinkedIn for a paper announcement, and it worked perfectly. About 3x more engagements than on Bluesky. Obviously, LinkedIn is a different culture, more formal and less chatty, but for professional things it works just fine. Can't believe it was there all the time, and we just did not use it
Several years ago, we established a "quantitative gene regulation" group on LinkedIn, around 1600 members, but somehow, the community was more active on Twitter, so we did not post in this group for years. May be it's time to revive it? www.linkedin.com/groups/3795224
Teif lab
Alexis Verger 🧬🧫🧪
Teif lab
Teif lab
Teif lab
Adhireksan et al, 2026. Linker histones consolidate heterogenous nucleosome fiber contacts by linking together multiple nucleosomes www.nature.com/articles/s41...
Sun et al, 2026. NuRD-enabled CTCF-TET crosstalk orchestrates epigenome reprogramming and genome architecture www.cell.com/molecular-ce...
