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Proudly presenting work from my student Liguo Wang, who systematically compared condensates formed by full-length MDPs to IDR-only systems.
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Unlike simplified IDR-only models, natural condensates with folded domains exhibit pronounced structural heterogeneity and attenuated dynamics, revealing folded domains as architectural keystones in n...
doi.org
Folded domains impose structural heterogeneity and attenuated dynamics in biomolecular condensates - Nature Communications
Siewert-Jan Marrink