Plant biologist | Proud and happy dad | Passionate about stress-resilient plants🌱, microbes🦠, and symbiotic nutrient interactions | From 🇲🇽 living in 🇪🇺
X: @leo_castanedo
Leo Castanedo
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Finally out in @Cellcellpress!
Proteins with long IDRs are prone to misfolding during protein synthesis.
This is prevented by mRNA 3′UTRs that act as mRNA-based IDR chaperones.
www.cell.com/cell/fulltex...
Highly conserved mRNA 3′ UTRs act as co-translational chaperones for intrinsically
disordered regions (IDRs), preventing inter-domain misfolding and enabling biogenesis
of fully active proteins.
📢 new preprint!
How do commensal bacteria establish themselves on plant roots despite plant immunity?
We identify Cpi1, a conserved membrane-anchored protease inhibitor in Pseudomonas that promotes early root colonization and modulates microbial community assembly.
www.biorxiv.org/cgi/content/...
A big thank you to @ceplas.bsky.social, @teamthomma.bsky.social, and @trr341.bsky.social for sponsoring our 🌿 team shirts, and to Helen Janssen for organizing and leading the Plantletics crew. 💪🏼
📸 Photo credits: Helen Janssen (not on Bluesky), @eellamas.bsky.social , and @antonkraege.bsky.social
Happy to share our work! 🍄🍇 Botrytis cinerea grapevine-specialized strains harbor a specific repertoire of transposons. While retrotransposon-derived small RNAs do not appear to play a significant role in virulence on grapevine, a new giant transposon—a #Starship— confers arsenic resistance.
Christine Mayr
Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature.
Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis.
doi.org/10.1038/s415...
Host killing by necrotrophs is really complex.
Using a 29-gene knockout series in Botrytis cinerea, we show that removing nearly all known cell death-inducing proteins and major phytotoxins is not sufficient to prevent host necrosis.
Check out the paper: www.biorxiv.org/content/10.6...
Here we show that low intra-microbiota antagonism underlies stable, protective barley root microbiota. Microbiota function cannot be predicted from beneficial traits of individual strains alone, but depends on compatibility among community members. #Microbiome #Plant
www.biorxiv.org/content/10.6...
Hiring: Junior Group Leader (f) in Protein Science — CRC 1664 SNP2Prot, MLU Halle. Lead your own group + budget, funded PhD, world-class protein-structure facilities. 5 yrs, E14. Apply by 7 July 2026. snp2prot.uni-halle.de #ProteinScience #SNP2Prot #AcademicJobs
Please RT:
Registration is ongoing for our International Symposium "Microbial Networking - from organelles to cross-kingdom communities" organized as highlight of the first funding period of CRC 1535 @mibinet.bsky.social
www.sfb1535.hhu.de/internationa...
@dfg.de, @hhu.de, @fz-juelich.de
Yesterday, Plantletics 🌿, the running group representing the Institute for Plant Sciences @unicologne.bsky.social, took part in the #UniLauf, and we had a fantastic time‼️
