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Microbiology | Cell Signaling | Structural Biology | Institute of Phototrophic Microbiology @hhu.de https://www.phototrophic-microbiology.hhu.de/en/ Central Metabolism Coordination by #PII & #cdiAMP & #cdiGMP & #Ca2+ signaling #Cyanobacteria
Khaled_Selim Lab









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🌲 We're hiring a postdoc! Join the Future Forests Excellence Cluster at Uni Freiburg to uncover the molecular basis of stress resilience in forest trees. Work with Douglas fir & sessile oak using epigenomics, RNA-seq, and more. 3-year position, TV-L 13. Apply now! 🧬🌿 uni-freiburg.de/stellenangeb...
Cryo-EM: the revolution continues journals.iucr.org/m/issues/202...
Join us for TPJ WEBINAR to feature our special issue on Plant structure biology @theplantjournal.bsky.social hosted by the amazing Editor-in-chief @katherinedenby.bsky.social Speakers: @cblikstad.bsky.social & @bjornppedersen.bsky.social & Clarisa Álvarez 30 June us02web.zoom.us/webinar/regi...
19d
Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com​​​​​​​​​​​​​​​​ 🌐 https://search.foldseek.com/folddisco
Now out in @pnas.org 🥳 "DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity" --> bad timing can kill you, even as a virus. www.pnas.org/doi/10.1073/... @spp2330.bsky.social, @mibinet.bsky.social, @dfg.de
1d
Membrane binding controls the ATPase cycle and localization of MinD in Bacillus subtilis doi.org/10.7554/eLif... - The final version of a long story! Biochemical analysis of MinD in vitro and in vivo (with SMLM). Credit goes to @drhelgon.bsky.social!
👋 We invite researchers based in Germany, Jordan, Egypt, Lebanon, Morocco, Oman, the Palestinian Territories, Qatar, Saudi Arabia, Syria, Tunisia, or the United Arab Emirates to our interdisciplinary Symposium. #FrontiersOfResearch 📅 13-16 November 2026 www.humboldt-foundation.de/en/apply/spo...
Day–night shifts in microbial activity affecting arsenic and iron in the rice rhizosphere -in @natgeosci.nature.com www.nature.com/articles/s41... #ChronoSky
Decoding the interactome for cyclic-di-AMP-producing enzyme diadenylate cyclase -in #mSystems journals.asm.org/doi/10.1128/...
News on the control of metabolism in Bacillus subtilis: #SubtiWiki www.sciencedirect.com/science/arti...
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Katrin Heer
Dynamic relocalization of MinD in Bacillus subtilis arises from membrane binding of monomers and dimers with membrane-triggered ATP hydrolysis, suggesting MinE-like activators are unnecessary for Min ...
doi.org
Membrane binding controls the ATPase cycle and localization of MinD in Bacillus subtilis
Khaled_Selim Lab
The increasing democratization and implementation of electron cryo-microscopy appears poised to drive a new revolution in digital structural biology.
journals.iucr.org
Cryo-EM: the revolution continues
Diurnal cycles in microbial reducer activity reveal synchronized mobilization of arsenic and iron in the rice rhizosphere, as shown by metatranscriptomic and biogeochemical analyses.
www.nature.com
Day–night shifts in microbial activity affecting arsenic and iron in the rice rhizosphere - Nature Geoscience
Mapping the DacA interactome reveals how environmental and intracellular cues tune c-di-AMP signaling to control stress adaptation, ion balance, and virulence traits in Streptococcus mutans. By identi...
journals.asm.org
Biosynthetic needs of a cell and the generation of precursors and energy in catabolic reactions must be faithfully balanced. Even in model organisms s…
www.sciencedirect.com
Decoding the interactome for cyclic-di-AMP-producing enzyme diadenylate cyclase | mSystems
Discovery of new mechanisms to control metabolism and homeostasis in Bacillus subtilis
Khaled_Selim Lab
Folddisco enables protein structural motif search in million scale databases.
www.nature.com
Structural motif search across the protein universe with Folddisco - Nature Biotechnology
Martin Steinegger 🇺🇦
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
PNAS
Marc Bramkamp
Julia Frunzke
Jörg Stülke
Humboldt-Stiftung
Ákos T Kovács
Ákos T Kovács
Happy to share our recent preprint: "DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity" www.biorxiv.org/content/10.6... @spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco
Cryo-EM: the revolution continues doi.org/10.1107/S205...
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🔈 New TPJ webinar with the @globalplantgpc.bsky.social 🌱 New Insights from Plant Structural Biology🌱 Explore how structural biology is advancing plant science With Clarisa Ester Álvarez, @cblikstad.bsky.social & @bjornppedersen.bsky.social 🗓️ June 30 ⏰ 15:00 CEST us02web.zoom.us/webinar/regi...
The increasing democratization and implementation of electron cryo-microscopy appears poised to drive a new revolution in digital structural biology.
Cryo-EM: the revolution continues
doi.org
Julia Frunzke
Martin Steinegger 🇺🇦
5d
Alexey Amunts
The Plant Journal