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I am delighted to be able to share that our latest paper arising from a project co-led by @drsarahboyle.bsky.social and me is now out in the world, published in AAAS Science Advances. www.science.org/doi/10.1126/...
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Compressive force drives PIEZO1-RHO-ROCK mechanotransduction and establishes an epigenetic memory that promotes tumor progression.
www.science.org
Compressive stress–driven Piezo1 activation and Rho-ROCK mechanotransduction promote tumor progression via epigenetic mechanical memory
Michael Samuel