Hu et al show that 2 transcription factors, MYT1 & ST18, have distinct, overlapping roles in human #betacell survival and secretory function under different metabolic stress, with transcriptional targets that are enriched for #diabetes risk genes link.springer.com/article/10.1... 🔓
Aims/hypothesis Genetic and environmental factors work together to cause islet beta cell failure, leading to type 2 diabetes. How these factors are integrated to regulate beta cells remains largely un...
