Islet amyloid formation upregulates StAR expression in beta cell mitochondria, leading to mitochondrial dysfunction and increased cell death #Islets #BetaCells #Mitochondria #DiabetesResearch link.springer.com/article/10.1... 🔓
Aims/hypothesis Loss of islet beta cell function and mass are critical in the pathogenesis of type 2 diabetes, a disease in which ~90% of individuals exhibit islet amyloid deposition. Amyloid deposits...
