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#HDAC9 & #innate immunity
Mar 24, 2025
Check out comments in @natrevimmunol.bsky.social & @cp-immunity.bsky.social
Mechanisms linking the #HDAC9 risk locus to arterial remodeling | phenotypic modulation of #VSMC & related phenotypes
Mar 24, 2025
1mo
Yaw Asare
Yaw Asare
Yaw Asare
Mar 15, 2025
The factors that modulate the inflammatory response in atherosclerosis are not well defined. In this issue of Immunity, Asare et al. examine the impact of a cis-regulatory element (CRE) that controls expression of HDAC9 and find that HDAC9-mediated…
dlvr.it
The CREscendoing promise of HDAC targeting to limit atherosclerosis
Immunity
www.cell.com/immunity/ful... - 👉ISD investigators now defined a mechanism whereby HDAC9 regulates activation of the NLRP3 inflammasome and developed a targeted anti-inflammatory approach for treating atherosclerosis. #HDAC9 #cell #immunity
Jan 29, 2025
Cardiovascular risk gene HDAC9 drives maladaptive vascular remodeling after arterial injury https://www.biorxiv.org/content/10.64898/2026.05.12.723753v1