Doctoral researcher @mpi-bio-fml.bsky.social and curious human being
De-coding brown algae 🍙
Erica Dinatale
Behind the scenes!
go.nature.com/4bYY8BM
TEs aren’t just genomic parasites, they’re also engines of genomic novelty.
Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion.
With @danielcroll.bsky.social & @guidopuccetti.bsky.social
🧬 www.nature.com/articles/s41...
#TEworldwide
Out now in @newphyt.bsky.social with @joannarifkin.bsky.social, @jotlovell.bsky.social, @spicybotrytis.bsky.social & more! Our high-quality pennycress pangenome is a striking example of genome architecture shaping different kinds of genomic variation, including some surprising centromeric movement
Now out!
We show that TEs can be horizontally transferred between fungal species via Starships. Once transferred, these TEs can become active, changing the genome organization and affecting the lifestyle of the recipient fungus.
www.nature.com/articles/s41...
@oggenfussursula.bsky.social #TEsky
DIAMOND DeepClust: an ultrafast clustering method for organizing the protein universe of life.
www.nature.com/articles/s41...
Does hidden protein biology live in the suboptimal alignment space?
When we align two divergent proteins, we usually trust a single optimal alignment. 🧬
But what if the real structural signal lies in the space of near-optimal solutions?
With EMERALD-UI you can unfold this perspective.
Our work on chromatin evolution in brown algae is finally out!
This is also my first "co-first author" paper!! I’m excited to share what we found 👇
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below!
doi.org/10.1126/scie...
Eukaryotic genomes harbor many forms of variation, including nucleotide diversity and structural polymorphisms, which experience natural selection and contribute to genome evolution and biodiversity...
In this study, the authors analysed a large genomic dataset to trace how jumping genes shaped the global spread of a major wheat pathogen and reveal bursts of activity over decades that drove adaptati...
A good read on a large virus...
Extensive array of endogenous giant viral elements in a polar alga shows dynamic transcriptional response to abiotic stress: Current Biology www.cell.com/current-biol...
DIAMOND DeepClust provides an ultra-fast clustering method for organizing the protein universe of life at low sequence identity, enabling large-scale dimensionality reduction and improving downstream ...
www.nature.com
Large mobile genetic elements known as Starships act as vehicles for transferring transposable elements (TEs) between fungi. Here, Griem-Krey et al. show that these ‘hitchhiking’ TEs can drive rapid e...
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...
Schultz et al. show that polar algae harbor extensive endogenous giant virus elements
that are transcriptionally active, stress responsive, and integrated into host regulatory
networks, highlighting v...
Chromatin plays a central role in gene regulation, but chromatin systems are only known for a few model species. This study analyses chromatin regulatory landscapes in brown algal lineages to elucidate their structural organization and evolution 🧪 www.nature.com/articles/s41...
Chromatin plays a central role in gene regulation, but chromatin systems are only known for a few model species. This study analyses chromatin regulatory landscapes in brown algal lineages to elucidat...
