Kilwein, M. D., Miller, P., Lee, K. Y., Osterfield, M., Mogilner, A., Shvartsman, S. Y., Gavis, E. R. (2025). Formation of Drosophila germ cells requires spatial patterning of phospholipids. Curr Biol, 35(7):1612-1621. www.cell.com/current-biol...
With mathematical modeling and experiments, Kilwein et al. show that Drosophila primordial
germ cells bud from the embryo by outward membrane buckling driven by actin polymerization.
Germ granules loc...