Pedersen, C. N., Yang, F., Ita, S., ..., Mortensen, O. V., Nissen, P., Shahsavar, A. (2024). Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site. J Neurochem, onlinelibrary.wiley.com/doi/10.1111/...
Atypical inhibitors of dopamine transporter lack the rewarding effects of psychostimulants and offer a promising strategy for the treatment of drug use disorders. In this study, we present the cryo-e...