Our lab studies ssDNA gaps as the cause of BRCAness and investigates how these gaps create a therapeutic window for sensitizing cancer cells to anti-cancer therapies.
Cantorlab
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Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S...
Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together! @albertociccia.bsky.social @labvincenzo.bsky.social
Cantorlab
Cantorlab
Happy to share a new publication on Mechanistic Coupling of Enzyme Activities at the Replisome in JBC. We #Traklab compare and contrast strategies used across organisms to coordinate the many enzymatic processes that occur during DNA replication. Hope it is helpful. doi.org/10.1016/j.jb...
9 days to go:
* 2 x open positions!
* Exceptional environment, competitive start-up package
* University of Toronto appointments
* Toronto has great (and peaceful) quality of life!
Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social
www.nokings.org
Enjoying Brisbane from TRI seminar to Felons brewery with Kum Kum Khanna and MathewJones.
UMASS Graduation-Congratulations Silvia!
www.nytimes.com/interactive/...
Keystone Symposia
Daniel Durocher
Looking forward to reading!
Cantorlab
Cantorlab
Cantorlab
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.
www.nature.com/naturecareer...
Please repost!
Cantorlab
Michael Trakselis
Cantorlab
Daniel Durocher
The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.
On June 14—Flag Day—Donald Trump wants tanks in the street and a made-for-TV display of dominance for his birthday. A spectacle meant to look like strength. But real power isn’t staged in Washington. ...
Excited to share our new pre-print. Direct, ensemble FRET assays developed by our lab reveal that assembly of Rad51 filaments at stalled replication sites via RPA/Rad51 exchange causes complete & irreversible PCNA unloading. Big implications for interplay between human DNA damage tolerance pathways
