#OpenAccess community-driven journal for peer-reviewed research in all areas of the life sciences. By EMBO Press (@embopress.org), Rockefeller University Press (@rupress.org), and Cold Spring Harbor Laboratory Press (@cshlpress.bsky.social).
Immunology collection: Luan & colleagues show that a lack of BCL6 expression in activated CD8 T cells or pharmacological BCL6 inhibition inhibits tumors. The findings suggest ways to improve the CD8 T cell function in cancer by changing their energy utilization @scripps.edu
Discover important benchmarking studies, resources, and methodologies.
Read articles in the Genetics, Genomics, and Epigenomics collection.
www.life-science-alliance.org/content/gene...
More in our Cancer Biology collection: Pipeline to evaluate YAP-TEAD inhibitors indicates TEAD inhibition represses NF2-mutant mesothelioma
life-science-alliance.org/content/canc...
How do T cells know when to stop? Our new 'scan and stop' assay reveals CD40 and CD70 as selective regulators of CD4+ and CD8+ T cell arrest on APCs, lowering the threshold for stable synapse formation. Check it out! www.life-science-alliance.org/content/9/8/...
Immunology Collection: MFN2 Q367H drives mtDNA release and inflammation, uncovering a new mechanism of MFN2-linked disease. @mitomorph.bsky.social
www.life-science-alliance.org/content/lsa-...
Read the full paper here: www.life-science-alliance.org/content/8/6/...
Read the paper here: www.life-science-alliance.org/content/9/1/...
Full paper 👉 www.life-science-alliance.org/content/8/10...
This study reveals that GPLD1 acts as a novel scavenger carrier that directly binds and delivers extracellular aberrant proteins, such as serum amyloid A1, to lysosomes for degradation via cell surface heparan sulfate.
@reviewcommons.org
www.life-science-alliance.org/content/9/8/...
