CNRS Research Director
Single molecule fluorescence & smFRET of membrane proteins.
Director of the Center for Structural Biology. (@cbsmontpellier.bsky.social).
I collect photons nights & days (in the wild & in the lab)
Biophysics & Astrophotography here
Emmanuel Margeat
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#RIP Pierre Chambon (1931-2026)
1963 PARP
1970 RNA Pol II
1975 Nucleosome
1977 Split genes
1980 Promoter
1983 enhancer
1986 Nuclear receptor
Another shot of yesterday's moonrise, above the Mediterranean sea.
Plage des Aresquiers, next to #Montpellier
#astrophotography
A new paper from the @cbsmontpellier.bsky.social !
"Paused in Translation: A Model for the Transcript Length-Dependent Impact of Ribosome-Targeting Antibiotics on Degrading mRNAs"
Moonrise, this morning. Etang des Aresquiers, next to #Montpellier
#astrophotography
New paper from the @cbsmontpellier.bsky.social
"CF2H: a cell-free two-hybrid platform for rapid protein binder screening "
now out in Nature Communications
www.nature.com/articles/s41...
And a version with the pink flamingos.
Etang des Aresquiers, next to #Montpellier
#astrophotography
Discover where single-molecule FRET is heading! Join us in Tutzing, Germany for the upcoming thematic meeting Single-Molecule FRET: The Next 30 Years from September 21-25, 2026. Abstract submission is now open!
The BPS Ambassador Program creates an international network of members who act as local resources in their respective countries, promoting biophysics and engaging the global community.
Apply to serve as a BPS Ambassador buff.ly/S6VwJmW
Alexis Verger ๐งฌ๐งซ๐งช
Emmanuel Margeat
Emmanuel Margeat
Center for Structural Biology (CBS Montpellier)
Center for Structural Biology (CBS Montpellier)
Faster and cheaper experimental screening methods will democratize and accelerate the identification of high-affinity binders with biomedical applications. Here the authors present Cell-Free Two-Hybri...
New paper out today in PRX Life!
We developed a stochastic transport model showing how antibiotic-induced ribosome pausing may trigger collective jamming on mRNA, with longer transcripts paying a disproportionate price.
Read it here! ๐
๐ doi.org/10.1103/vrqp...
You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
Moonrise, this morning. Etang des Aresquiers, next to #Montpellier
#astrophotography