PhD student in (developmental/comp)neuroscience. Cossart lab (INMED, Marseille). track2p.github.io
Jure Majnik
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Now published - the #BANC! A full central nervous system (CNS) connectome of a limbed animal at single-synapse resolution, enabling us to follow sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS. #neuroscience. Video by @quorumetrix.bsky.social 1/18
Hello #world, meet 1,000× Expansion Microscopy.
A small gel would grow to the size of an Olympic swimming pool, while amino-acid-scale distances become visible with ordinary light microscopy.
Led by Helena Hu from @eboyden3.bsky.social's lab, in collab with us.
Story: www.biorxiv.org/content/10.6...
Video
“Using an optical backfilling method relying on photoactivable GFP, we generate a whole-brain map of all neurons sending axons towards the spinal cord. This approach reveals far more SPNs than previously described through conventional strategies.”
Bonkers work from @wyartlab.bsky.social 🐟🧠
As someone interested in both genetics & neural activity, I appreciate the common challenge of linking causal function to system-level understanding.
This excellent review by @jamesbriscoe.bsky.social & Maizels shows a way forward for gene networks in development
pubmed.ncbi.nlm.nih.gov/41803457/
Our latest: Minimal essential requirements for neural tube self-organisation
How does a single cell give rise to a tissue with the right cell types in the right proportions?
We deconstruct and rebuild a self-organising tissue from first principles
A thread🧵
www.biorxiv.org/content/10.6...
#Science #Biologie
🦇 « L’évolution des mécanismes du développement »
🖥️ Les vidéos du colloque organisé par le Pr @denisduboule.bsky.social, titulaire de la chaire #Évolution du développement et des #génomes, sont disponibles !
👉 https://tinyurl.com/39p4h5pn
Cortical folding patterns are encoded in the geometry of the unfolded neocortex. https://www.biorxiv.org/content/10.64898/2026.06.05.730475v1
How are two embryos alike?
As we collect spatio-temporal microscopy data, we want to quantify variability in the timing of key developmental events.
Alignment of multiple recordings is a core engineering challenge here and we suggest a solution; read about it:
www.biorxiv.org/content/10.6...
📣 new preprint multimodal atlas. Imaging + scRNA, 57M cells. 🧬🔬
Cells are complex dynamical systems — but most ways we measure them destroy them. We asked: how does live imaging compare to scRNA-seq, the field’s gold std?
The answer surprised us 🧵
www.biorxiv.org/content/10.6...
Wei-Chung Allen Lee
Ali Shaib
The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...
Gene regulatory networks (GRNs) explain how the genome controls cellular behaviour and tissue morphogenesis, serving to connect molecular mechanism to functional output. Single-cell technologies now p...
Quantitative comparison of morphogenesis across individuals remains a fundamental challenge, as developing embryos vary in shape, orientation and developmental tempo. Moreover, real-time three-dimensi...
