Nature Reviews Bioengineering, Published online: 03 June 2026; doi:10.1038/s44222-026-00466-yAn article in Science Advances reports the development of a mini human cervix-on-a-chip. The model supports the growth of cervical cells and vaginal microbiota as well as inoculation with sexually transmitted infections, enabling investigation of complex host–microbiota–pathogen relationships.