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Senior Scientist 👨🏽‍🔬 @dome-vienna.bsky.social, @univie.ac.at 🇲🇽🇪🇺(🇦🇹🇫🇷🇪🇸) Symbionts, bacteria, insects, leeches, viruses, bioinformatics, evolution, genomics. Opinions are my very own. #SymbioSky https://besymblab.univie.ac.at/ https://ecoevo.social/@amanzanom
Alejandro Manzano Marín









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.. And no evidence of relaxed selection on protein-coding genes shared between Buchnera and Serratia, suggesting that the presence of Serratia does not exacerbate genome erosion in Buchnera even on redundant metabolic genes! ...
.. To our surprise, both bacterial lineages show similar substitution rates, contrasting what we have observed in, for example, Leafhopper's symbiotic systems (Nasuia and Sulcia). Genome variations within and between aphid species indicate strong purifying selection acting on both symbionts..
.. Thus, we show that these symbionts have coevolved under comparable selective constraints and demographic events at least within this clade of Cinara species, that originated ~25 Million years ago
#Aphids typically rely on the obligate #symbiont #Buchnera, but several lineages have acquired additional co-obligate symbionts, most commonly #Serratia symbiotica. Through phylogenetic analyses, we found that a clade of Cinara aphids shows strict cospeciation between aphids and both endosymbionts..
#Genome-resolved #metagenomics reveals conserved, flexible and emerging #symbioses across global #leafhoppers doi.org/10.64898/202... #SymbioSky
New work out! #Coevolution and synchronized evolutionary rates in #aphid dual #endosymbiot sytems w/ Jess, Emmanuelle, Armelle, & co. doi.org/10.64898/202... @cbgpmontpellier.bsky.social @inrae-france.bsky.social @cemess.bsky.social @dome-vienna.bsky.social @univie.ac.at #SymbioSky #MicroSky
SypC, a #symbiont #outerMembraneVesicle protein, impacts the development of the #squid – #vibrio partnership doi.org/10.1073/pnas... #SymbioSky
Just published! Check out our review of the Nucleocytoviricota infection cycle. Great teamwork! @mkrupovic.bsky.social @willemsenanouk.bsky.social @fischerlab.bsky.social @puffy-virus.bsky.social
New Work out! A multilayered network reveals the centrality of newly discovered #Nucleocytoviricota in wastewater treatment plant communities w/ @dominikluecking.bsky.social & @amanzanom.bsky.social doi.org/10.64898/202... @erc.europa.eu @univie.ac.at @dome-vienna.bsky.social 1/4
With Eugene Koonin, we wrote a rather comprehensive review on the origin, evolution and organization of the #virosphere. We describe all 10 viral realms and the logic behind them, and so much more. Check it out! comptes-rendus.academie-sciences.fr/biologies/ar...
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SypC, a symbiont outer membrane vesicle protein, impacts the development of the squid–vibrio partnership | PNAS
Bacterial outer membrane vesicles (OMVs) and the cargo they carry are increasingly recognized as a means of communication between microbial symbion...
doi.org
Alejandro Manzano Marín
Alejandro Manzano Marín
Alejandro Manzano Marín
Alejandro Manzano Marín
Alejandro Manzano Marín
Alejandro Manzano Marín
Alejandro Manzano Marín
Hugo Bisio
Anouk Willemsen
Mart Krupovic